Biotechnician – Therapeutic gene delivery

Are you interested in vivo gene therapy and enthusiastic for improving in vivo viral delivery to the right cells? Apply to develop gene therapy approaches in one of the most innovative centres in the Netherlands.

Dit ga je doen

We offer a position as biotechnician in development of in vivo gene therapy with a focus on the nervous system within UMC Utrecht. To this end, you will work in a division overarching team that strives to accelerate clinical development of gene therapies by focusing on one of the current main obstacles in this field: efficient delivery of gene products to the right organs and cell types of interest (by designing minimal promoters and enhancers, specific coat proteins). Your role is to grow high titer AAV stocks, deliver these and other gene delivery methods to mice and test the efficacy of gene delivery in vivo using FACS sorting and immunohistochemistry. 

Hier ga je werken

The position is embedded within the Department of Translational Neuroscience of UMC Utrecht.  The project focusses on building an in-house viral vector production platform within UMC Utrecht to support development of gene therapy. In addition to this embedding, the technician will be team member of the UMCU gene-therapy delivery platform and thus closely collaborate with the other UMC Utrecht groups working on gene therapies, in particular with Innovation Center for Advanced Therapies (ICAT) and Regenerative Medicine Center Utrecht (RMCU).

Dit neem je mee

• You are a biotechnician with affinity for viral vector development, production  and delivery.
• You have knowledge about cell culture and virus purification, cloning, flow cytometry, immunohistochemistry and handling mice
• You have interest in delivery of gene therapy in vivo, preferably in mice.
• You have the ability to think analytically, problem-solving skills, and a drive to succeed.
• You have the ambition to work in an innovation driven, highly collaborative and fast paced environment.
• You have skills to work independently as well as collaborate with other team members with interdisciplinary background and social skills for fruitful interactions.

Dit bieden we jou

• A salary between € 2.975 en € 4.214 gross per month (salary scale 7M), based on full-time employment (36 hours). 
• We offer a position for a period of two years.
• Year-end bonus of 8.3% and holiday allowance of 8%. 
• Pension insurance with ABP. We take care of approximately 70% of the monthly contribution. 
• 100% public transport reimbursement. Are you coming on foot, by bike or by car? You will then receive a reimbursement of € 0.18 per km (by car up to a max. of 40 km one way). 
• Possibilities to develop yourself personally and professionally. 
• The option to select additional employment benefits in exchange for gross salary, such as purchasing a bicycle and memberships.